National Geographic : 1998 Aug
REZULIN®: FOR IMPROVED CONTROL OF TYPE 2 DIABETES. Rezulin (troglitazone) isa once-a -day pill for diabetes that helps your body use its blood sugar control. Rezulin not well controlled with diet pills known as sulfonylureas, bloodsugar* body * insulin L*. i ** . DIABETIC BODY CELLS DON'T RESPOND EFFICIENTLY TO INSULIN AND BLOCK OUT BLOOD SUGAR. own insulin for improved may be used for patients and exercise alone, oral or insulin. REZULIN WORKS WITHIN THE CELL TO HELP INSULIN LET BLOOD SUGAR IN. Can Reduce And Perhaps Eliminate The Need For Insulin Injections. Because Rezulin makes improved use of insulin, it can make a difference if insulin injections are part of your type 2 diabetes treatment. With Rezulin, you may be able to decrease the amount of insulin or the number of injections you're taking. You may even be able to eliminate injections altogether. Increases The Effectiveness Of Many Oral Medications. Your doctor may find that Rezulin provides better blood sugar control when added to diabetes pills known as sulfonylureas such as Amaryl,* Glucotrol XL,* Glynase* PresTab,* glipizide, or glyburide. Ask Your Doctor If Rezulin Is Right For You. Rezulin can provide a useful treatment option for millions of people with type 2 diabetes. Please be aware that Rezulin should not be used by patients with type 1 diabetes. Rezulin, like all the diabetes medications currently available to treat type 2 diabetes, has been associated with side effects. Although they are not usually serious, you should discuss these possibilities with your doctor. In rare cases, Rezulin has been associated with serious liver problems, which are generally reversible, but in very rare instances, these have resulted in liver failure and fatality. Your doctor can advise you about the new recommendations for regular liver monitoring with Rezulin, which will require routine blood tests. The most common side effects reported in medical studies were similar to placebo (a tablet with no medicine); they include infection (22% placebo vs. 18% Rezulin), headache (11% placebo vs. 11% Rezulin), and pain (14% placebo vs. 10% Rezulin). Talk to your doctor immediately if you have nausea, vomiting, stomach pain, fatigue, lack of appetite, dark urine, or yellowing of the skin (jaundice), as these may be signs or symptoms of a liver problem. Adhere to any dietary, exercise or weight-loss recommendations made by your doctor, and test your blood sugar regularly. As with any drug, tell your doctor or healthcare professional about any other medications you may be taking. If your therapy includes Rezulin and pills known as sulfonylureas, there is a chance you may incur a manageable weight gain. If you are a premenopausal woman who is not ovulating, you should know Rezulin therapy may result in resumption of ovulation, thus putting you at risk for pregnancy. Over 900,00 People Have Begun Using Rezulin To Help Manage Diabetes. And the number keeps growing. Your doctor or healthcare professional is the best source for finding out if Rezulin is right for you. To know more, see the important information on the adjacent page, and call: Toll Free 1-888-900-TYPE2. ONCE-DAILY * Amaryl is a registered trademark of Hoechst Marion Roussel; Glucotrol XL is a registered trademark of Pfizer, Inc.; Glynase and PresTab are registered trademarks of Pharmacia & Upjohn. PD-168-NJ -2381-A1(068) 801014 ©1998 Parke-Davis Pharmaceuticals Limited TROGLITAZONE ASK YOUR DOCTOR ABOUT THE REZULIN DIFFERENCE. Please see important additional information on adjacent page. IBERZUI AFTER REZULIN I .i%..