National Geographic : 1944 Jul
Smallpox Scourges a Mandan Village in the 1837 Epidemic Which Nearly Exterminated the Tribe Some of these upper Missouri River Indians were stricken after boarding a trading boat on which two white men were suffering from thedisease. The epidemic spread throughout the tribe. The Indians had no way of combatting smallpox, and whole families succumbed rapidly. Inafewmonths, only 23men, 40women, and 65 children had survived. Most of these were disfigured. They were soon absorbed by other tribes and the Mandans ceased toexist asanation.